Spravato (Esketamine)
At Brainiac Behavioral Health, our Spravato® (esketamine) treatment offers new hope for individuals struggling with treatment-resistant depression. We understand that traditional medications don’t work for everyone, which is why we provide this FDA-approved option in a safe, supportive environment designed to meet your unique needs.
Spravato® is administered as a nasal spray under the supervision of our trained providers, who carefully monitor your treatment sessions for safety and effectiveness. This innovative therapy targets the brain in a different way than traditional antidepressants, helping to relieve symptoms of depression more quickly for many patients.
Whether you’ve tried multiple medications without success or are searching for a new path forward, Spravato® may be the breakthrough you’ve been waiting for. At Brainiac Behavioral Health, we are committed to offering cutting-edge treatments that restore hope, balance, and lasting wellness.
"Spravato® offers new hope for those living with treatment-resistant depression—providing relief where traditional medications have not, and opening the door to healing and renewed balance."
What is Spravato®?
Spravato® (esketamine) is an FDA-approved treatment for adults with treatment-resistant depression—a form of depression that hasn’t improved with standard antidepressant medications. Unlike traditional oral medications, Spravato® is administered as a nasal spray in a clinical setting under the supervision of a trained provider.
Spravato® works differently than most antidepressants by targeting the brain’s NMDA receptor, which plays a role in mood regulation. Many patients experience faster relief from depressive symptoms compared to traditional treatments. Sessions are carefully monitored for safety, and patients remain in a comfortable, supportive environment during and after administration.
At Brainiac Behavioral Health, Spravato® is part of our commitment to offering advanced, evidence-based therapies that provide hope and healing for those who have struggled to find lasting relief.
How Does Spravato Work?
Spravato® (esketamine) works differently than traditional antidepressants. While most antidepressants target serotonin, norepinephrine, or dopamine, Spravato® acts on the NMDA receptor in the brain, which is involved in mood regulation and neural connections. By stimulating this receptor, Spravato® helps increase the release of glutamate—a neurotransmitter that plays a key role in learning, memory, and emotional regulation.
This process is believed to create new pathways in the brain, improving communication between nerve cells and allowing for faster symptom relief in individuals with treatment-resistant depression. Many patients notice improvements within hours to days, compared to the weeks or months often required for standard medications.
At Brainiac Behavioral Health, Spravato® treatments are administered in a safe, supportive clinical setting where your response and well-being are closely monitored during each session.
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Spravato® FAQ
Q: What is Spravato®?
A: Spravato® (esketamine) is an FDA-approved nasal spray treatment for adults with treatment-resistant depression—meaning depression that hasn’t improved with at least two other antidepressant medications.
Q: How does Spravato® work?
A: Spravato® targets the NMDA receptor in the brain, which works differently from traditional antidepressants. It helps increase glutamate activity, creating new brain connections that can improve mood regulation and bring faster relief from depressive symptoms.
Q: Who is a good candidate for Spravato®?
A: Spravato® is recommended for adults with major depressive disorder who have not found relief from standard antidepressant medications. A full evaluation with our providers will determine if this treatment is right for you.
Q: How is Spravato® administered?
A: Spravato® is given as a nasal spray in our office under the supervision of a trained provider. Each session includes monitoring for about two hours to ensure your safety and comfort.
Q: How soon will I feel results?
A: Many patients notice improvements within hours to days of their first treatment, while others may see changes gradually over several weeks. Individual responses vary.
Q: Are there side effects?
A: Common side effects can include dizziness, nausea, drowsiness, or a temporary feeling of dissociation. These effects typically wear off the same day, and patients must arrange for a ride home after treatment.
Q: Is Spravato® covered by insurance?
A: Many insurance providers do cover Spravato® for treatment-resistant depression. Our team can help verify your benefits and guide you through the approval process.
Q: How long does treatment last?
A: Treatment plans vary, but Spravato® is usually administered twice a week for the first month, then gradually reduced in frequency as symptoms improve. Your provider will customize your schedule based on your progress.